| FPDc | |||||||||
| Actual value (ms) | % of Pre | ||||||||
| Concentration (μM) | n | Pre | 10 min | 4 h | 24 h | Pre | 10 min | 4 h | 24 h |
| Vehicle | 4 | 316.9 ± 35.7 | 319.5 ± 35.1 | 312.9 ± 30.6 | 318.8 ± 31.6 | 100 | 101.0 ± 0.8 | 99.3 ± 1.8 | 101.2 ± 3.0 |
| 1 | 3 | 228.4 ± 15.4 | 228.9 ± 15.0 | 228.6 ± 30.6 | 247.8 ± 20.7# | 100 | 100.3 ± 0.3 | 100.3 ± 1.1 | 108.2 ± 2.1# |
| 3 | 4 | 249.7 ± 27.6 | 254.2 ± 26.6* | 262.6 ± 24.8# | 306.8 ± 20.2# | 100 | 102.1 ± 0.7# | 105.9 ± 2.6 | 126.1 ± 12.5 |
| 10 | 3 | 270.6 ± 53.3 | 277.8 ± 53.0# | 292.8 ± 60.4 | 425.4 ± 63.5* | 100 | 103.0 ± 1.1 | 108.0 ± 4.1 | 162.0 ± 13.7* |